

NFL:
How will Isaac Prince's injury affect SF's Week 1 offensive line projections and fantasy outlook for blockers and RBs?
Qwiket AI:
Prince's status shifts Week 1 line projections to include Burford or Zakelj at tackle, with Pleasants ready as a depth option. If the line stabilizes, blockers and RBs maintain baseline fantasy expectations; if instability persists, run-game efficiency could dip and pass protection may push QB and WR/TE projections lower until the line settles.
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San Francisco 49ers: